Hendrik Luesch Selected Research

apratoxin S10

1/2019	Development of apratoxin S10 (Apra S10) as an anti-pancreatic cancer agent and its preliminary evaluation in an orthotopic patient-derived xenograft (PDX) model.
12/2017	Correction to "Apratoxin S10, a Dual Inhibitor of Angiogenesis and Cancer Cell Growth To Treat Highly Vascularized Tumors".
10/2017	Apratoxin S10, a Dual Inhibitor of Angiogenesis and Cancer Cell Growth To Treat Highly Vascularized Tumors.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Hendrik Luesch Research Topics

Disease

45	Neoplasms (Cancer) 04/2024 - 01/2002
8	Breast Neoplasms (Breast Cancer) 01/2021 - 08/2010
7	Colonic Neoplasms (Colon Cancer) 01/2022 - 03/2010
6	Colorectal Neoplasms (Colorectal Cancer) 04/2024 - 11/2011
4	Neoplasm Metastasis (Metastasis) 01/2021 - 09/2017
3	Inflammation (Inflammations) 10/2023 - 02/2013
3	Triple Negative Breast Neoplasms 01/2021 - 11/2017
3	Hypoxia (Hypoxemia) 10/2018 - 01/2016
3	Neuroblastoma 04/2013 - 03/2007
2	Pancreatic Neoplasms (Pancreatic Cancer) 01/2021 - 01/2019
2	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2020 - 01/2008
2	Lung Diseases (Lung Disease) 01/2016 - 02/2013
2	Carcinoma (Carcinomatosis) 08/2015 - 09/2010
2	Adenocarcinoma 08/2015 - 09/2010
1	Multiple Sclerosis 10/2023
1	Starvation 10/2021
1	Noncommunicable Diseases 09/2021
1	Pathologic Neovascularization 08/2021
1	Prostatic Neoplasms (Prostate Cancer) 01/2021
1	Glioblastoma (Glioblastoma Multiforme) 01/2020
1	Brain Neoplasms (Brain Tumor) 01/2020
1	Lung Neoplasms (Lung Cancer) 01/2020
1	Central Nervous System Diseases (CNS Diseases) 01/2020
1	Colitis 01/2020
1	Opioid-Related Disorders (Opiate Addiction) 01/2020
1	Choroidal Neovascularization 01/2019
1	Retinal Neovascularization 01/2019
1	Infections 10/2018
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2018

Drug/Important Bio-Agent (IBA)

8	largazoleIBA 08/2021 - 11/2010
4	DepsipeptidesIBA 01/2023 - 02/2013
4	Histone Deacetylases (Histone Deacetylase)IBA 08/2021 - 11/2010
4	Phosphotransferases (Kinase)IBA 10/2020 - 07/2009
4	Pancreatic Elastase (Elastase)IBA 01/2020 - 02/2013
4	Peptide Hydrolases (Proteases)FDA Link 07/2018 - 01/2016
3	dolastatin 10IBA 02/2024 - 01/2002
3	RNA (Ribonucleic Acid)IBA 10/2023 - 01/2020
3	Histone Deacetylase InhibitorsIBA 08/2021 - 11/2010
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2020 - 01/2011
3	apratoxin S10IBA 01/2019 - 10/2017
3	tyrosine receptor (receptor, tyrosine)IBA 01/2019 - 07/2009
3	Histones (Histone)IBA 08/2014 - 11/2010
3	apratoxin AIBA 11/2011 - 06/2008
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 10/2023 - 03/2017
2	ChromatinIBA 01/2022 - 03/2011
2	LuciferasesIBA 01/2022 - 03/2007
2	Proteasome Endopeptidase Complex (Proteasome)IBA 09/2021 - 01/2018
2	TubulinIBA 01/2021 - 01/2020
2	apratoxin S4IBA 01/2021 - 01/2019
2	Proteins (Proteins, Gene)FDA Link 01/2021 - 01/2008
2	Sulfhydryl Compounds (Thiols)IBA 01/2020 - 01/2017
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2019 - 11/2011
2	Small Interfering RNA (siRNA)IBA 10/2018 - 11/2017
2	Anti-Bacterial Agents (Antibiotics)IBA 10/2018 - 01/2016
2	Cysteine (L-Cysteine)FDA Link 11/2017 - 06/2008
2	CathepsinsIBA 11/2017 - 01/2016
2	symplostatin 1IBA 03/2015 - 04/2003
2	Oxidoreductases (Dehydrogenase)IBA 04/2013 - 03/2007
2	quinone (benzoquinone)IBA 04/2013 - 03/2007
2	NAD (NADH)IBA 04/2013 - 03/2007
2	Sunitinib (Sutent)FDA Link 09/2011 - 01/2011
2	Bevacizumab (Avastin)FDA Link 09/2011 - 01/2011
2	Sorafenib (BAY 43-9006)FDA Link 09/2011 - 01/2011
1	AcetyltransferasesIBA 04/2024
1	Thioredoxin-Disulfide ReductaseIBA 04/2024
1	Histone-Lysine N-MethyltransferaseIBA 04/2024
1	MetalsIBA 04/2024
1	chaetocinIBA 04/2024
1	dysidazirineIBA 03/2022
1	Carboxylic AcidsIBA 03/2022
1	IronIBA 10/2021
1	AlkaloidsIBA 09/2021
1	aaptamineIBA 09/2021
1	AndrogensIBA 01/2021
1	homoserine lactoneIBA 01/2021
1	LipocalinsIBA 01/2020
1	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2020
1	ProdrugsIBA 01/2020
1	VincamineIBA 01/2020
1	Yohimbine (Yocon)IBA 01/2020
1	CalciumIBA 01/2020
1	dolastatin 15IBA 01/2020
1	Antineoplastic Agents (Antineoplastics)IBA 01/2019
1	CytokinesIBA 01/2019
1	Oxygen (Dioxygen)IBA 01/2019
1	Thiamine (Aneurin)FDA Link 10/2018
1	Kallikreins (Kallikrein)IBA 07/2018
1	Dihydrotachysterol (AT 10)IBA 07/2018
1	Serine Proteases (Serine Protease)IBA 07/2018
1	molassamideIBA 01/2018
1	Laxaphycin AIBA 01/2018
1	Cardiac GlycosidesIBA 01/2018
1	Peptides (Polypeptides)IBA 01/2018
1	UbiquitinIBA 01/2018
1	Biomarkers (Surrogate Marker)IBA 11/2017
1	grassystatin FIBA 11/2017
1	Cystatin CIBA 11/2017

Therapy/Procedure

11	Therapeutics 01/2022 - 11/2010
2	Drug Therapy (Chemotherapy) 01/2021 - 01/2018
1	Lasers (Laser) 01/2019